P.R.I.T. ExpoCube with P.R.I.T. ControlUnit

P.R.I.T. ® ExpoCube is an unrivaled exposure system for testing of airborne substances by means of alternative in-vitro methods.

Unique selling points of this innovative, patented technology include the following:

Compatibility with commercial cell culture membranes and multi-well plate inserts

  • supports culture inserts from Falcon, Costar and currently 12-well format
  • direct transfer of well plate from incubator into the ExpoCube®

Prevention of exposure artifacts from unwanted side reactions

  • complete separation of culture medium and exposure atmospheres.
  • no false-positive results due to secondary exposures

Efficient, uniform, and gentle exposure thanks to CFD (computational fluid dynamics)-optimized geometry of flow paths

  • better understanding of the procedure
  • optimized exposure efficiency while preserving cellular viability

Novel design concept opening up unrivaled experimental possibilities

  • multi-well-based design
  • consistently modular concept of the overall system supporting e.g. physical preprocessing of the airborne test substance and assignment of individual cultures to particular exposure groups.

High particulate deposition efficiency without cell-damaging effect

  • increased deposition efficiency of very small particles through thermophoresis
  • no requirement for physical preprocessing of the airborne test substance, e.g. electrostatic charging

On-line observation of cell cultures during the exposure by live-cell imaging

  • innovative design enables observation of the exposed cell cultures during the exposure using fluorescence-based live-cell staining.
  • completely new generation of experimental designs in in-vitro testing of airborne substances through direct use and read-out of reporter gene-transfected cells
  • new possibilities in kinetic analyses, direct read-out of cell toxicity without posterior incubation

Reliable and low maintenance

  • two components P.R.I.T.® ExpoCube and P.R.I.T.® ControlUnit provide the complete technical functionality
  • reliable operation, easy-to-use (simple set-up), involving low maintenance
  • easy to transport and ready for exposure tests right after insertion of a multi-well plate with cells.